Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background

Author:

Weuts An11,Voet Thierry1,Verbeeck Jelle11,Lambrechts Nathalie11,Wirix Evelyne11,Schoonjans Luc1,Danloy Sophie1,Marynen Peter1,Froyen Guy11

Affiliation:

1. Human Genome Laboratory, VIB Center for the Biology of Disease, 2Human Genome Laboratory, KU Leuven, 3Laboratory for Reproductive Genomics, Center for Human Genetics, KU Leuven and 4Thromb-X, Department of Molecular and Cellular Medicine, B-3000 Leuven, Belgium

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference41 articles.

1. Human artificial chromosomes for gene delivery and the development of animal models;Kazuki;Mol. Ther.,2011

2. Prospects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy;Perez-Luz;J. Biomed. Biotechnol.,2010

3. Artificial and engineered chromosomes: developments and prospects for gene therapy;Grimes;Chromosoma,2005

4. A minimal CENP-A core is required for nucleation and maintenance of a functional human centromere;Okamoto;EMBO J.,2007

5. Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA;Lam;Proc. Natl Acad. Sci. USA,2006

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