1. Food Biotechnology Laboratory, Graduate Program in Biotechnology, University of Vale do Taquari - Univates , Lajeado, RS, ZC 95914-014 , Brazil
2. Cell Culture Laboratory, Graduate Program in Biotechnology, University of Vale do Taquari - Univates , Lajeado, RS, ZC 95914-014 , Brazil
3. Institute of Pharmacy, Pharmaceutical/Medicinal Chemistry and Tübingen Center for Academic Drug Discovery, Eberhard Karls University Tübingen , Tübingen, ZP 72072 , Germany