Fiber intake and health in people with chronic kidney disease

Author:

Su Guobin1234ORCID,Qin Xindong2,Yang Changyuan2ORCID,Sabatino Alice5ORCID,Kelly Jaimon T67,Avesani Carla Maria89,Carrero Juan Jesus3ORCID

Affiliation:

1. National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Clinical Research Center for Kidney Disease, Department of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China

2. Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital, The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China

3. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

4. Department of Global Public Health, Health Systems and Policy, Karolinska Institutet, Stockholm, Sweden

5. Department of Nephrology, Parma University Hospital, Parma, Italy

6. Centre for Online Health, The University of Queensland, Brisbane, Australia

7. Centre for Health Services Research, The University of Queensland, Brisbane, Australia

8. Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden

9. Medical Unit Clinical Nutrition, Karolinska University Hospital, Stockholm, Sweden

Abstract

Abstract Emerging evidence suggests that diet, particularly one that is rich in dietary fiber, may prevent the progression of chronic kidney disease (CKD) and its associated complications in people with established CKD. This narrative review summarizes the current evidence and discusses the opportunities for increasing fiber intake in people with CKD to improve health and reduce disease complications. A higher consumption of fiber exerts multiple health benefits, such as increasing stool output, promoting the growth of beneficial microbiota, improving the gut barrier and decreasing inflammation, as well decreasing uremic toxin production. Despite this, the majority of people with CKD consume less than the recommended dietary fiber intake, which may be due in part to the competing dietary potassium concern. Based on existing evidence, we see benefits from adopting a higher intake of fiber-rich food, and recommend cooperation with the dietitian to ensure an adequate diet plan. We also identify knowledge gaps for future research and suggest means to improve patient adherence to a high-fiber diet.

Funder

Swedish Research Council

Karolinska Institutet’s

National Nature Science Foundation of China

China Postdoctoral Science Foundation

Science and Technology Research Fund

Guangdong provincial hospital of Chinese medicine, China

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

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