The Associations Between Sleep Disturbance, Psychological Dysfunction, Pain Intensity, and Pain Interference in Children with Chronic Pain

Author:

Solé Ester12,Sharma Saurab34ORCID,Ferreira-Valente Alexandra56ORCID,Pathak Anupa3,Sánchez-Rodríguez Elisabet12,Jensen Mark P6,Miró Jordi12ORCID

Affiliation:

1. Universitat Rovira i Virgili, Unit for the Study and Treatment of Pain – ALGOS, Research Center for Behavior Assessment (CRAMC), Department of Psychology, Catalonia, Spain

2. Institut d’Investigació Sanitària Pere Virgili; Universitat Rovira i Virgili, Catalonia, Spain

3. Centre for Musculoskeletal Outcomes Research, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand

4. Department of Physiotherapy, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal

5. William James Center for Research, ISPA – Instituto Universitário, Lisbon, Portugal

6. Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA

Abstract

Abstract Objectives This study aimed to better understand the associations between both sleep disturbance and psychological dysfunction (i.e., anxiety and depressive symptoms, and anger), and pain intensity and pain interference, in a sample of children with chronic pain. Design Cross-sectional design. Methods Three hundred and forty-two children with chronic pain (8–18 years) completed measures assessing pain intensity, pain interference, sleep disturbance, anxiety, depressive symptoms, and anger. Regression analyses examined the direct, interaction (with sex), and mediation effects of sleep quality and psychological dysfunction on pain intensity and interference. Results Sleep disturbance was significantly associated with both pain intensity and pain interference. However, measures of psychological dysfunction were associated significantly only with pain interference. Sex did not moderate these associations. The measures of psychological dysfunction mediated the associations between sleep disturbance and pain interference but not those between sleep disturbance and pain intensity. Conclusions The results confirmed significant cross-sectional associations between both sleep disturbance and psychological dysfunction and pain outcomes in children with chronic pain. Future research to test for causal associations is warranted.

Funder

Spanish Ministry of Economy, Industry and Competitiveness

Publisher

Oxford University Press (OUP)

Subject

Anesthesiology and Pain Medicine,Neurology (clinical),General Medicine

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