Recent advances in nanotherapeutics for the treatment of burn wounds

Author:

Huang Rong1,Hu Jun2,Qian Wei3,Chen Liang4,Zhang Dinglin15ORCID

Affiliation:

1. Department of Chemistry, College of Basic Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, China

2. Department of Neurology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China

3. Institute of Burn Research, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China

4. Department of plastic surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China

5. State Key Laboratory of Trauma, Burn and Combined Injury, Chongqing, 400038, China

Abstract

Abstract Moderate or severe burns are potentially devastating injuries that can even cause death, and many of them occur every year. Infection prevention, anti-inflammation, pain management and administration of growth factors play key roles in the treatment of burn wounds. Novel therapeutic strategies under development, such as nanotherapeutics, are promising prospects for burn wound treatment. Nanotherapeutics, including metallic and polymeric nanoformulations, have been extensively developed to manage various types of burns. Both human and animal studies have demonstrated that nanotherapeutics are biocompatible and effective in this application. Herein, we provide comprehensive knowledge of and an update on the progress of various nanoformulations for the treatment of burn wounds.

Funder

State Key Laboratory of Trauma, Burn and Combined Injury, Third Military Medical University

Publisher

Oxford University Press (OUP)

Subject

Critical Care and Intensive Care Medicine,Dermatology,Biomedical Engineering,Emergency Medicine,Immunology and Allergy,Surgery

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