Development of a bivalent food poisoning vaccine: augmented antigenicity of the C-terminus ofClostridium perfringensenterotoxin by fusion with the B subunit ofEscherichia coliShiga toxin 2

Author:

Hosomi Koji1,Hinenoya Atsushi2,Suzuki Hidehiko1,Nagatake Takahiro1,Nishino Tomomi1,Tojima Yoko1,Hirata So-ichiro13,Matsunaga Ayu1,Kondoh Masuo4,Yamasaki Shinji2,Kunisawa Jun13456

Affiliation:

1. Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan

2. Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan

3. Department of Microbiology and Immunology, Graduate School of Medicine, Kobe University, Hyogo, Japan

4. Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan

5. Graduate School of Medicine and Graduate School of Dentistry, Osaka University, Suita, Osaka, Japan

6. Division of Mucosal Vaccines, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Funder

Research Fellowship for Young Scientists

Ministry of Education, Culture, Sports, Science and Technology

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Ministry of Health, Labour and Welfare

Science and Technology Research Promotion Program for Agriculture, Forestry, Fisheries and Food Industry

Terumo Foundation for Life Sciences and Arts

Ono Medical Research Foundation

Cannon Foundation

Publisher

Oxford University Press (OUP)

Subject

Immunology,General Medicine,Immunology and Allergy

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