Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
Author:
Publisher
Oxford University Press (OUP)
Subject
Genetics(clinical),Genetics,Molecular Biology,General Medicine
Link
http://academic.oup.com/hmg/article-pdf/26/18/3531/19688172/ddx238.pdf
Reference74 articles.
1. Protein dynamism and evolvability;Science,2009
2. Mutational effects and the evolution of new protein functions;Nat. Rev. Genet,2010
3. The stability effects of protein mutations appear to be universally distributed;J. Mol. Biol,2007
4. Stability-mediated epistasis constrains the evolution of an influenza protein;Elife,2013
5. Chaperonin overexpression promotes genetic variation and enzyme evolution;Nature,2009
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