Network Analysis of Protein Adaptation: Modeling the Functional Impact of Multiple Mutations-Reference-Cited by-同舟云学术

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Network Analysis of Protein Adaptation: Modeling the Functional Impact of Multiple Mutations

Published:2018-03-07 Issue:6 Volume:35 Page:1507-1519
ISSN:0737-4038
Container-title:Molecular Biology and Evolution
language:en
Short-container-title:

Author:

Beleva Guthrie Violeta¹,Masica David L¹,Fraser Andrew¹,Federico Joseph¹,Fan Yunfan¹,Camps Manel²,Karchin Rachel¹³

Affiliation:

1. Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD

2. Department of Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA

3. Department of Oncology, Johns Hopkins University Medicine, Baltimore, MD

Funder

National Science Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Link

http://academic.oup.com/mbe/article-pdf/35/6/1507/25091467/msy036.pdf

Reference76 articles.

1. A standard numbering scheme for the class A beta-lactamases;Ambler;Philos Trans R Soc Lond B Biol Sci,1991

2. On the (un)predictability of a large intragenic fitness landscape;Bank;Proc Natl Acad Sci U S A.,2016

3. Phylogenetic analysis shows that the OXA beta-lactamase genes have been on plasmids for millions of years;Barlow;J Mol Evol.,2002

4. The Protein Data Bank;Berman;Nucleic Acids Res.,2000

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