Functional characteristics of novel pancreatic Pax6 regulatory elements
Author:
Affiliation:
1. MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, UK
2. Centre for Mammalian Synthetic Biology, University of Edinburgh, Edinburgh EH9 3FF, UK
Funder
Medical Research Council
Publisher
Oxford University Press (OUP)
Subject
Genetics(clinical),Genetics,Molecular Biology,General Medicine
Link
http://academic.oup.com/hmg/article-pdf/27/19/3434/25741238/ddy255.pdf
Reference70 articles.
1. Systematic localization of common disease-associated variation in regulatory DNA;Maurano;Science,2012
2. Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes;Ashery-Padan;Dev. Biol.,2004
3. Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas;St-Onge;Nature,1997
4. Aniridia-associated translocations, DNase hypersensitivity, sequence comparison and transgenic analysis redefine the functional domain of PAX6;Kleinjan;Hum. Mol. Genet.,2001
5. Opposing actions of Arx and Pax4 in endocrine pancreas development;Collombat;Genes Dev.,2003
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