Amino acid position 37 of HLA-DRβ1 affects susceptibility to Crohn’s disease in Asians

Author:

Han Buhm12,Akiyama Masato3,Kim Kyung-Kon24,Oh Hyunjung5,Choi Hyunchul5,Lee Cue Hyunkyu12,Jung Seulgi5,Lee Ho-Su5,Kim Emma E126,Cook Seungho12,Haritunians Talin7,Yamazaki Keiko89,Park Sang Hyoung10,Ye Byong Duk10,McGovern Dermot P B7,Esaki Motohiro11,Kawaguchi Takaaki1213,Khor Seik-Soon14,Taylor Kent D15,Rotter Jerome I15,Suzuki Yasuo16,Matsui Toshiyuki17,Motoya Satoshi18,Bang So-Young19,Kim Tae-Hwan19,Momozawa Yukihide9,Kamatani Yoichiro320,Tokunaga Katsushi14,Kubo Michiaki21,Okada Yukinori32223,Yang Suk-Kyun10,Song Kyuyoung5

Affiliation:

1. Department of Medicine, Seoul National University College of Medicine, Seoul, Korea

2. Department of Convergence Medicine, University of Ulsan College of Medicine & Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea

3. Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

4. Convergence Medicine Research Center and Biomedical Research Center, AILS, Asan Medical Center, Seoul, Korea

5. Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Korea

6. Department of Chemistry, Seoul National University, Seoul, Korea

7. The F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA

8. Division of Genomic Epidemiology and Clinical Trials, Clinical Trials Research Center, Nihon University School of Medicine, Tokyo, Japan

9. Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

10. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

11. Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

12. Division of Gastroenterology, Department of Medicine, TokyoYamate Medical Center, Tokyo, Japan

13. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

14. Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

15. Institute for Translational Genomics and Population Sciences,Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical CenterTorrance, CA, USA

16. Department of Internal Medicine, Faculty of Medicine, Toho University, Chiba, Japan

17. Department of Gastroenterology, Fukuoka University,Chikushi Hospital, Fukuoka, Japan

18. Department of Gastroenterology, Sapporo-Kosei General Hospital, Sapporo, Japan

19. Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea

20. Center for Genomic Medicine, Kyoto University Graduate School of Medicine,Sakyo-ku, Kyoto, Japan

21. RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

22. Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan

23. Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Osaka, Japan

Funder

Korea Institute of Science and Technology

Korea Health Industry Development

Ministry of Health and Welfare

Ministry of Science and Technology

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

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