Genetics and pathogenesis of inflammatory bowel disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature10209.pdf
Reference100 articles.
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2. Anderson, C. A. et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genet. 43, 246–252 (2011). This study identifies 29 new loci containing genes that reinforce the contribution of epithelial barrier function, intracellular defence and cytokine-dependent signalling in ulcerative colitis, and it also reports genetic overlap with Crohn's disease.
3. Spehlmann, M. E. et al. Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study. Inflamm. Bowel Dis. 14, 968–976 (2008).
4. Yazdanyar, S., Kamstrup, P. R., Tybjaerg-Hansen, A. & Nordestgaard, B. G. Penetrance of NOD2/CARD15 genetic variants in the general population. Can. Med. Assoc. J. 182, 661–665 (2010).
5. Monick, M. M. et al. Identification of an autophagy defect in smokers' alveolar macrophages. J. Immunol. 185, 5425–5435 (2010).
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