ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci

Author:

Stacey David1ORCID,Fauman Eric B2,Ziemek Daniel3,Sun Benjamin B1,Harshfield Eric L14,Wood Angela M1,Butterworth Adam S1,Suhre Karsten5,Paul Dirk S1ORCID

Affiliation:

1. MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK

2. Pfizer Worldwide Research & Development, Genome Sciences & Technologies, Cambridge, MA 02142, USA

3. Pfizer Worldwide Research & Development, Inflammation & Immunology, 14167 Berlin, Germany

4. Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK

5. Department of Physiology and Biophysics, Weill Cornell Medicine-Qatar, PO 24144, Doha, Qatar

Funder

Wellcome Trust

Medical Research Council

British Heart Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference49 articles.

1. The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog);MacArthur;Nucleic Acids Res.,2017

2. Association analyses based on false discovery rate implicate new loci for coronary artery disease;Nelson;Nat. Genet.,2017

3. Biological insights from 108 schizophrenia-associated genetic loci;Ripke;Nature,2014

4. 10 years of GWAS Discovery: Biology, function, and translation;Visscher;Am. J. Hum. Genet.,2017

5. Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans;Ardlie;Science,2015

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