Pro12Ala Polymorphism of the PPARG2 Gene Is Associated with Type 2 Diabetes Mellitus and Peripheral Insulin Sensitivity in a Population with a High Intake of Oleic Acid

Author:

Soriguer Federico,Morcillo Sonsoles,Cardona Fernando,Rojo-Martínez Gemma,de la Cruz Almaráz María,de la Soledad Ruiz de Adana María,Olveira Gabriel,Tinahones Francisco,Esteva Isabel

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference45 articles.

1. Peroxisome proliferator-activated receptors: nuclear control of metabolism;Desvergne;Endocr Rev.,1999

2. Pro12Ala substitution in the human peroxisome proliferator-activated receptor gamma2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index;Deeb;Nat Genet.,1998

3. Molecular scanning of the human peroxisome proliferator activated receptor gamma gene in diabetic Caucasians: identification of a Pro12Ala PPARgamma 2 missense mutation;Yen;Biochem Biophys Res Commun.,1997

4. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes;Altshuler;Nat Genet.,2000

5. Studies of the Pro12Ala Polymorphism of the PPAR-gamma gene in the Danish MONICA Cohort: Homozygosity of the Ala Allele Confers a Decreased Risk of the Insulin Resistance Syndrome;Frederiksen;J Clin Endocrinol Metab.,2002

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