Pandemic Uropathogenic Fluoroquinolone-resistant Escherichia coli Have Enhanced Ability to Persist in the Gut and Cause Bacteriuria in Healthy Women-Reference-Cited by-同舟云学术

Pandemic Uropathogenic Fluoroquinolone-resistant Escherichia coli Have Enhanced Ability to Persist in the Gut and Cause Bacteriuria in Healthy Women

Published:2019-07-04 Issue:5 Volume:70 Page:937-939
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Tchesnokova Veronika L¹²,Rechkina Elena²,Chan Diana¹,Haile Helen Ghirmai¹,Larson Lydia¹,Ferrier Kendra¹,Schroeder David W¹,Solyanik Thalia¹,Shibuya Spencer¹,Hansen Kelly³⁴,Ralston James D³⁴,Riddell Kim⁴,Scholes Delia³⁴,Sokurenko Evgeni V¹

Affiliation:

1. Department of Microbiology, University of Washington School of Medicine

2. ID Genomics, Inc

3. Kaiser Permanente Washington Health Research Institute

4. Kaiser Permanente Washington, Seattle

Abstract

Abstract We report that fluoroquinolone-resistant Escherichia coli are found in feces of 8.8% of healthy women, with most bacteria belonging to pandemic multidrug-resistant ST131-H30R or ST1193 clonal groups. Moreover, these highly uropathogenic clonal groups demonstrate an especially prolonged gut persistence and high rate of bacteriuria without documented urinary tract infection.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciz547/28997063/ciz547.pdf

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