Phylogenomic Analysis of Extraintestinal Pathogenic Escherichia coli Sequence Type 1193, an Emerging Multidrug-Resistant Clonal Group

Author:

Johnson Timothy J.12,Elnekave Ehud3,Miller Elizabeth A.13,Munoz-Aguayo Jeannette2,Flores Figueroa Cristian2,Johnston Brian45,Nielson Daniel W.6,Logue Catherine M.7,Johnson James R.4

Affiliation:

1. Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA

2. Mid-Central Research and Outreach Center, University of Minnesota, Willmar, Minnesota, USA

3. Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, Minnesota, USA

4. Minneapolis Veterans Health Care System, Minneapolis, Minnesota, USA

5. Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA

6. Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA

7. Department of Population Health, University of Georgia, Athens, Georgia, USA

Abstract

The fluoroquinolone-resistant sequence type 1193 (ST1193) of Escherichia coli , from the ST14 clonal complex (STc14) within phylogenetic group B2, has appeared recently as an important cause of extraintestinal disease in humans. Although this emerging lineage has been characterized to some extent using conventional methods, it has not been studied extensively at the genomic level.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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