An evidence-based approach to globally assess the covariate-dependent effect of the MTHFR single nucleotide polymorphism rs1801133 on blood homocysteine: a systematic review and meta-analysis

Author:

Jin Huifeng1,Cheng Haojie1,Chen Wei1,Sheng Xiaoming2,Levy Mark A1,Brown Mark J1,Tian Junqiang1

Affiliation:

1. Department of Research and Development, USANA Health Science, Salt Lake City, UT;

2. Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, UT

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference15 articles.

1. Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase;Yamada;Proc Natl Acad Sci USA,2001

2. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase;Frosst;Nat Genet,1995

3. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease;Seshadri;N Engl J Med,2002

4. Homocysteine and cardiovascular disease: a review of the evidence;Wierzbicki;Diab Vasc Dis Res,2007

5. Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort;Russo;J Nutr,2003

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