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Unsolved mystery: the role of BRCA1 in DNA end-joining

  • Published:2016-05-10 Issue:S1 Volume:57 Page:i18-i24
  • ISSN:0449-3060
  • Container-title:Journal of Radiation Research
  • language:en
  • Short-container-title:J Radiat Res

Author:

Saha Janapriya,Davis Anthony J.

Funder

National Institutes of Health

Cancer Prevention Research Institute of Texas

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Radiology Nuclear Medicine and imaging,Radiation

Reference57 articles.

1. Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations;Tirkkonen;Cancer Res,1997

2. Breast Cancer Risk and the DNA Double-Strand Break End-Joining Capacity of Nonhomologous End-Joining Genes Are Affected by BRCA1

3. Fidelity of DNA double-strand break repair in heterozygous cell lines harbouring BRCA1 missense mutations

4. Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts;Zhong;Cancer Res,2002

5. Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells

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