Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells

Author:

Xu Xiaoling,Weaver Zoë,Linke Steven P,Li Cuiling,Gotay Jessica,Wang Xin-Wei,Harris Curtis C,Ried Thomas,Deng Chu-Xia

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference43 articles.

1. Double indemnity;Brugarolas;Nat. Med,1997

2. Transcriptional activation by BRCA1;Chapman;Nature,1996

3. BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner;Chen;Cancer Res,1996

4. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells;Chen;Mol. Cell,1998

5. p53 mutations in BRCA1-associated familial breast cancer;Crook;Lancet,1997

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