1. Institute for Cellular Medicine Newcastle University, Newcastle upon Tyne NE2 4HH, UK
2. Rheumatology Department, James Cook Hospital, Middlesbrough TS4 3BW, UK
3. The Bone Clinic Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
4. Gosforth Memorial Medical Centre, Newcastle upon Tyne NE3 1TX, UK
5. NIHR Newcastle Biomedical Research Centre, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK