Late-Gestation Rat Myometrial Cells Express Multiple Isoforms of Phospholipase A2 That Mediate PCB 50-Induced Release of Arachidonic Acid with Coincident Prostaglandin Production

Author:

Brant Kelly,Loch Caruso Rita

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference60 articles.

1. Abe, A., Hiraoka, M., Wild, S., Wilcoxen, S. E., Paine, R., 3rd, and Shayman, J. A. (2004). Lysosomal phospholipase A2 is selectively expressed in alveolar macrophages. J. Biol. Chem.279,42605–42611.

2. Akiba, S., Mizunaga, S., Kume, K., Hayama, M., and Sato, T. (1999). Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells. J. Biol. Chem.274,19906–19912.

3. Arslan, A., and Zingg, H. H. (1996). Regulation of COX-2 gene expression in rat uterus in vivo and in vitro. Prostaglandins52,463–481.

4. ATSDR (2000). Toxicological Profile for Polychlorinated Biphenyls (PCBs). U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Atlanta, GA.

5. Bae, J., Peters-Golden, M., and Loch-Caruso, R. (1999). Stimulation of pregnant rat uterine contraction by the polychlorinated biphenyl (PCB) mixture aroclor 1242 may be mediated by arachidonic acid release through activation of phospholipase A2 enzymes. J. Pharmacol. Exp. Ther.289,1112–1120.

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