High-Throughput Screening to Evaluate Inhibition of Bile Acid Transporters Using Human Hepatocytes Isolated From Chimeric Mice
Author:
Affiliation:
1. Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, Kanagawa 251-8555, Kanagawa, Japan
2. Drug Safety Research and Evaluation, Takeda Pharmaceutical Company Limited, Cambridge, Massachusetts 02139, USA
Abstract
Publisher
Oxford University Press (OUP)
Subject
Toxicology
Link
http://academic.oup.com/toxsci/advance-article-pdf/doi/10.1093/toxsci/kfz229/30703241/kfz229.pdf
Reference65 articles.
1. Evaluating the role of multidrug resistance protein 3 (MDR3) inhibition in predicting drug-induced liver injury using 125 pharmaceuticals;Aleo;Chem. Res. Toxicol.,2017
2. Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells;Antherieu;Hepatology,2013
3. Interaction of oral antidiabetic drugs with hepatic uptake transporters: Focus on organic anion transporting polypeptides and organic cation transporter 1;Bachmakov;Diabetes,2008
4. Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3);Baldes;Eur. J. Pharm. Biopharm.,2006
5. Quantification of drug-induced inhibition of canalicular cholyl-l-lysyl-fluorescein excretion from hepatocytes by high content cell imaging;Barber;Toxicol. Sci.,2015
Cited by 14 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Control Compounds for Preclinical Drug-Induced Liver Injury Assessment: Consensus-driven systematic review by the ProEuroDILI Network;2023-11-09
2. Drug transporter expression and activity in cryopreserved human hepatocytes isolated from chimeric TK-NOG mice with humanized livers;Toxicology in Vitro;2023-08
3. Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease;Journal of Traditional and Complementary Medicine;2023-07
4. Modeling drug-induced liver injury: current status and future prospects;Expert Opinion on Drug Metabolism & Toxicology;2022-09-02
5. Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives;European Journal of Drug Metabolism and Pharmacokinetics;2022-07-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3