Measures of BSEP Inhibition In Vitro Are Not Useful Predictors of DILI
Author:
Affiliation:
1. Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, California
Funder
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Toxicology
Link
http://academic.oup.com/toxsci/article-pdf/162/2/499/24474152/kfx284.pdf
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3. BDDCS applied to over 900 drugs;Benet;AAPS J,2011
4. Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States;Chalasani;Gastroenterology,2008
5. Evaluation of DILI predictive hypotheses in early drug development;Chan;Chem. Res. Toxicol,2017
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