1. Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford , Old Road Campus , Oxford OX3 7BN , UK
2. MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital , Oxford OX3 9DS , UK
3. Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford , Old Road Campus , Oxford OX3 7BN , UK