The Galaxy platform for accessible, reproducible, and collaborative data analyses: 2024 update

Author:

,Abueg Linelle Ann L,Afgan Enis,Allart Olivier,Awan Ahmed H,Bacon Wendi A,Baker Dannon,Bassetti Madeline,Batut Bérénice,Bernt Matthias,Blankenberg Daniel,Bombarely Aureliano,Bretaudeau Anthony,Bromhead Catherine J,Burke Melissa L,Capon Patrick K,Čech Martin,Chavero-Díez María,Chilton John M,Collins Tyler J,Coppens Frederik,Coraor Nate,Cuccuru Gianmauro,Cumbo Fabio,Davis John,De Geest Paul F,de Koning Willem,Demko Martin,DeSanto Assunta,Begines José Manuel Domínguez,Doyle Maria A,Droesbeke Bert,Erxleben-Eggenhofer Anika,Föll Melanie C,Formenti Giulio,Fouilloux Anne,Gangazhe Rendani,Genthon Tanguy,Goecks Jeremy,Beltran Alejandra N Gonzalez,Goonasekera Nuwan A,Goué Nadia,Griffin Timothy J,Grüning Björn AORCID,Guerler Aysam,Gundersen Sveinung,Gustafsson Ove Johan Ragnar,Hall Christina,Harrop Thomas W,Hecht Helge,Heidari Alireza,Heisner Tillman,Heyl Florian,Hiltemann Saskia,Hotz Hans-Rudolf,Hyde Cameron J,Jagtap Pratik D,Jakiela Julia,Johnson James E,Joshi Jayadev,Jossé Marie,Jum’ah Khaled,Kalaš Matúš,Kamieniecka Katarzyna,Kayikcioglu Tunc,Konkol Markus,Kostrykin Leonid,Kucher Natalie,Kumar Anup,Kuntz Mira,Lariviere Delphine,Lazarus Ross,Bras Yvan Le,Corguillé Gildas Le,Lee Justin,Leo Simone,Liborio Leandro,Libouban Romane,Tabernero David López,Lopez-Delisle Lucille,Los Laila S,Mahmoud Alexandru,Makunin Igor,Marin Pierre,Mehta Subina,Mok Winnie,Moreno Pablo A,Morier-Genoud François,Mosher Stephen,Müller Teresa,Nasr Engy,Nekrutenko AntonORCID,Nelson Tiffanie M,Oba Asime J,Ostrovsky Alexander,Polunina Polina V,Poterlowicz Krzysztof,Price Elliott J,Price Gareth R,Rasche Helena,Raubenolt Bryan,Royaux Coline,Sargent Luke,Savage Michelle T,Savchenko Volodymyr,Savchenko Denys,Schatz Michael C,Seguineau Pauline,Serrano-Solano Beatriz,Soranzo Nicola,Srikakulam Sanjay Kumar,Suderman Keith,Syme Anna E,Tangaro Marco Antonio,Tedds Jonathan A,Tekman Mehmet,Cheng (Mike) Thang Wai,Thanki Anil S,Uhl Michael,van den Beek Marius,Varshney Deepti,Vessio Jenn,Videm Pavankumar,Von Kuster Greg,Watson Gregory R,Whitaker-Allen Natalie,Winter Uwe,Wolstencroft Martin,Zambelli Federico,Zierep Paul,Zoabi Rand

Abstract

Abstract Galaxy (https://galaxyproject.org) is deployed globally, predominantly through free-to-use services, supporting user-driven research that broadens in scope each year. Users are attracted to public Galaxy services by platform stability, tool and reference dataset diversity, training, support and integration, which enables complex, reproducible, shareable data analysis. Applying the principles of user experience design (UXD), has driven improvements in accessibility, tool discoverability through Galaxy Labs/subdomains, and a redesigned Galaxy ToolShed. Galaxy tool capabilities are progressing in two strategic directions: integrating general purpose graphical processing units (GPGPU) access for cutting-edge methods, and licensed tool support. Engagement with global research consortia is being increased by developing more workflows in Galaxy and by resourcing the public Galaxy services to run them. The Galaxy Training Network (GTN) portfolio has grown in both size, and accessibility, through learning paths and direct integration with Galaxy tools that feature in training courses. Code development continues in line with the Galaxy Project roadmap, with improvements to job scheduling and the user interface. Environmental impact assessment is also helping engage users and developers, reminding them of their role in sustainability, by displaying estimated CO2 emissions generated by each Galaxy job.

Funder

NIH

National Science Foundation

Horizon Europe

Biodiversity, Circular Economy and Environment

German Federal Ministry of Education and Research, BMBF

Ministry of Science, Research and the Arts Baden-Württemberg

Australian BioCommons

Australian Government

Bioplatforms Australia

Australian Research Data Commons

Queensland Government

Publisher

Oxford University Press (OUP)

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