White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease

Author:

Araque Caballero Miguel Ángel1,Suárez-Calvet Marc23,Duering Marco1,Franzmeier Nicolai1,Benzinger Tammie45,Fagan Anne M456,Bateman Randall J456,Jack Clifford R7,Levin Johannes28,Dichgans Martin129,Jucker Mathias10,Karch Celeste5611,Masters Colin L12,Morris John C45,Weiner Michael13,Rossor Martin14,Fox Nick C14,Lee Jae-Hong15,Salloway Stephen16,Danek Adrian28,Goate Alison1718,Yakushev Igor19,Hassenstab Jason20,Schofield Peter R2122,Haass Christian239,Ewers Michael1

Affiliation:

1. Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany

2. German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany

3. Biomedical Center, Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany

4. Department of Radiology, Washington University in St Louis, St Louis, MO, USA

5. Knight Alzheimer’s Disease Research Center, Washington University in St. Louis, St. Louis, MO, USA

6. Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO, USA

7. Department of Radiology, Mayo Clinic, Rochester, MN, USA

8. Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany

9. Munich Cluster for Systems Neurology (SyNergy), Munich, Germany

10. Hertie Institute for Clinical Brain Research, Tübingen, Germany and German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany

11. Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA

12. The Florey Institute, The University of Melbourne, Parkville, Victoria, Australia

13. University of California at San Francisco, San Francisco, CA94143, USA

14. Dementia Research Centre, University College London, Queen Square, London, UK

15. Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea

16. Department of Neurology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA

17. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA

18. Ronald M. Loeb Center for Alzheimer’s Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA

19. Department of Nuclear Medicine, Technical University of Munich, Munich, Germany

20. Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA

21. Neuroscience Research Australia, Barker Street Randwick, Sydney, Australia

22. School of Medical Sciences, University of New South Wales, Sydney, Australia

Funder

ERC

Alzheimer Forschung Initiative

National Institute for Health Research University College London Hospitals Biomedical Research Centre

MRC Dementias Platform UK

Dominantly Inherited Alzheimer’s Network

DIAN

National Institute on Aging

NIA

German Center for Neurodegenerative Diseases

DZNE

Raul Carrea Institute for Neurological Research

FLENI

Research and Development Grants for Dementia

Japan Agency for Medical Research and Development

AMED

Korea Health Technology R&D Project

Korea Health Industry Development Institute

KHIDI

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

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