1. Institute for Genetics, University of Cologne , Cologne 50931 , Germany
2. Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) , Cologne 50931 , Germany
3. Max Planck Institute for Biology of Ageing , Cologne 50931 , Germany
4. in vivo Research Facility, Medical Faculty and University Hospital Cologne, University of Cologne , Cologne 50931 , Germany
5. Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne , Cologne 50931 , Germany
6. Center for Molecular Medicine (CMMC), University of Cologne , Cologne 50931 , Germany