1. Royal Berkshire Hospital, Royal Berkshire Hospitals NHS Foundation Trust , RG1 5AN Reading , UK
2. Oxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust , OX3 9DU Oxford , UK
3. Oxford Biomedical Research Centre, Oxford University Hospitals , OX3 9DU Oxford , UK
4. Division of Cardiovascular Medicine, Radcliffe Department of Medicine, OX3 9DU University of Oxford , UK