Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay
Author:
Affiliation:
1. Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, USA
Funder
Ionis Pharmaceuticals
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/47/3/1110/27853692/gky1260.pdf
Reference62 articles.
1. Phosphorothioates, essential components of therapeutic oligonucleotides;Eckstein;Nucleic Acid Ther.,2014
2. Physicochemical properties of phosphorothioate oligodeoxynucleotides;Stein;Nucleic Acids Res.,1988
3. Cellular uptake and trafficking of antisense oligonucleotides;Crooke;Nat. Biotech.,2017
4. Structural determinants for the interactions of chemically modified nucleic acids with the Stabilin-2 clearance receptor;Gaus;Biochemistry,2018
5. Receptor-Mediated uptake of phosphorothioate antisense oligonucleotides in different cell types of the liver;Miller;Nucleic Acid Ther.,2018
Cited by 98 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. DNA/RNA heteroduplex technology with cationic oligopeptide reduces class-related adverse effects of nucleic acid drugs;Molecular Therapy - Nucleic Acids;2024-09
2. Physiological platelet aggregation assay to mitigate drug-induced thrombocytopenia using a microphysiological system;Scientific Reports;2024-06-19
3. Sequence- and Structure-Dependent Cytotoxicity of Phosphorothioate and 2′-O-Methyl Modified Single-Stranded Oligonucleotides;Nucleic Acid Therapeutics;2024-06-01
4. Nucleic Acid Therapeutics: Successes, Milestones, and Upcoming Innovation;Nucleic Acid Therapeutics;2024-04-01
5. Favorable efficacy and reduced acute neurotoxicity by antisense oligonucleotides with 2′,4′-BNA/LNA with 9-(aminoethoxy)phenoxazine;Molecular Therapy - Nucleic Acids;2024-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3