Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver
Author:
Affiliation:
1. Department of Biochemistry, University of Nebraska, Lincoln, Nebraska.
2. Ionis Pharmaceuticals, Carlsbad, California.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry
Link
http://www.liebertpub.com/doi/pdf/10.1089/nat.2017.0709
Reference85 articles.
1. Phosphorothioates, Essential Components of Therapeutic Oligonucleotides
2. Physicochemical properties of phospborothioate oligodeoxynucleotides
3. Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages
4. Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions
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