Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity-Reference-Cited by-同舟云学术

Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity

Published:2018-12-04 Issue: Volume: Page:
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

O’Reilly Daniel¹,Kartje Zachary J²,Ageely Eman A²,Malek-Adamian Elise¹,Habibian Maryam¹,Schofield Annabelle¹,Barkau Christopher L³,Rohilla Kushal J³,DeRossett Lauren B²,Weigle Austin T²,Damha Masad J¹,Gagnon Keith T²³

Affiliation:

1. Department of Chemistry, McGill University, Montreal, Quebec H3A 0B8, Canada

2. Department of Chemistry & Biochemistry, Southern Illinois University, Carbondale, Illinois 62901, USA

3. Department of Biochemistry & Molecular Biology, School of Medicine, Southern Illinois University, Carbondale, Illinois 62901, USA

Funder

National Science and Engineering Council of CANADA

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gky1214/26988227/gky1214.pdf

Reference66 articles.

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4. Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements;Mojica;J. Mol. Evol.,2005

5. CRISPR provides acquired resistance against viruses in prokaryotes;Barrangou;Science,2007

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