To Induce Immune Reconstitution Inflammatory Syndrome or Suppress It: The Spectrum of Mycobacterium genavense in the Antiretroviral Era-Reference-Cited by-同舟云学术

To Induce Immune Reconstitution Inflammatory Syndrome or Suppress It: The Spectrum of Mycobacterium genavense in the Antiretroviral Era

Published:2020-06-18 Issue:2 Volume:72 Page:315-318
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Manion Maura¹^ORCID,Lynn Niamh²,Pei Luxin¹,Hammoud Dima A³,Laidlaw Elizabeth¹,Roby Gregg¹,Metzger Dorinda¹,Mejia Yolanda⁴,Lisco Andrea¹,Zelazny Adrian¹,Holland Steve¹,Vachon Marie-Louise⁵,Scherer Matthew⁶,Bergin Colm²,Sereti Irini¹

Affiliation:

1. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA

2. St James’s Hospital, Dublin, Ireland

3. Center for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA

4. Leidos, Frederick, Maryland, USA

5. Centre hospitalier universitaire de Quebec–Université Laval, Quebec City, Quebec, Canada

6. Division of Infectious Diseases, Department of Internal Medicine, Columbia University Irving Medical Center, New York, New York, USA

Abstract

Abstract Mycobacterium genavense is a challenging opportunistic pathogen to diagnose and manage in patients with human immunodeficiency virus (HIV). Persistent immunosuppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses. We describe 3 cases of M. genavense in patients with HIV representing the spectrum between disease burden and strength of immune response.

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciaa753/33674691/ciaa753.pdf

Reference13 articles.

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2. Infection with a novel, unidentified mycobacterium;Böttger;N Engl J Med,1990