Genome stability is guarded by yeast Rtt105 through multiple mechanisms
Author:
Affiliation:
1. CNRS UMR7258, INSERM U1068, Aix-Marseille Université UM105, Institut Paoli-Calmettes, CRCM, Marseille, France
2. Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France
Abstract
Funder
Ligue Nationale Contre le Cancer
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/genetics/advance-article-pdf/doi/10.1093/genetics/iyaa035/36179639/iyaa035.pdf
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3. RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends;Audry;EMBO J,2015
4. The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes;Azvolinsky;Genes Dev,2006
5. Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks;Bando;J Biol Chem,2009
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1. The COMPASS subunit Spp1 protects nascent DNA at the Tus/Ter replication fork barrier by limiting DNA availability to nucleases;Nature Communications;2023-09-05
2. The COMPASS subunit Spp1 protects nascent DNA at stalled replication fork barrier by limiting DNA availability to nucleases;2022-12-13
3. Rtt105 regulates RPA function by configurationally stapling the flexible domains;Nature Communications;2022-09-02
4. Rtt105 configurationally staples RPA and blocks facilitated exchange and interactions with RPA-interacting proteins;2022-02-05
5. Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA;Proceedings of the National Academy of Sciences;2021-06-17
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