High Risk of Plasmodium vivax Malaria Following Splenectomy in Papua, Indonesia

Author:

Kho Steven1,Andries Benediktus2,Poespoprodjo Jeanne R234,Commons Robert J1,Shanti Putu A I3,Kenangalem Enny23,Douglas Nicholas M1,Simpson Julie A5,Sugiarto Paulus6,Anstey Nicholas M1,Price Ric N17ORCID

Affiliation:

1. Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia

2. Timika Malaria Research Program, Papuan Health and Community Development Foundation, Timika, Papua

3. Rumah Sakit Umum Daerah Kabupaten Mimika, Timika, Papua

4. Pediatric Research Office, Department of Pediatrics, University of Gadjah Mada, Yogyakarta, Indonesia

5. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Victoria, Australia

6. Rumah Sakit Mitra Masyarakat, Timika, Papua, Indonesia

7. Center for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom

Abstract

In Papua, splenectomized individuals have greater risk of malaria in the 12 months following splenectomy but not of mortality. Malaria risk was higher for Plasmodium vivax than P. falciparum. Early radical cure and prophylaxis are warranted in malaria endemic areas.

Funder

Wellcome Trust

Australian National Health and Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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