Screening for Ocular Candidiasis Among Patients With Candidemia: Is It Time to Change Practice?

Author:

O’Donnell Matthew1,Eller Andrew W2,Waxman Evan L2,Clancy Cornelius J3,Nguyen M Hong13

Affiliation:

1. University of Pittsburgh Medical Center, Division of Infectious Diseases , Pittsburgh, PA , USA

2. Department of Ophthalmology, University of Pittsburgh , Pittsburgh, PA , USA

3. Department of Medicine, University of Pittsburgh , Pittsburgh, PA , USA

Abstract

Abstract Ocular candidiasis (OC) complicates approximately 10% of candidemia and carries potentially severe morbidity. There are conflicting recommendations about the need for routine funduscopic examinations of candidemic patients. Indirect funduscopy is accurate and safe in diagnosing OC, and positive findings change recommended treatment. However, conclusive evidence that treatment changes improve outcomes is lacking. Bringing perspectives as infectious diseases physicians and ophthalmologists, we review controversies about OC and endorse routine screening during candidemia. We acknowledge difficulties in obtaining inpatient ophthalmologic consults and recommend studies to evaluate digital fundus photography and teleophthalmology as an alternative to funduscopic examinations by ophthalmologists in asymptomatic patients.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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