Genome editing for disease resistance in pigs and chickens
Author:
Affiliation:
1. The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK
Publisher
Oxford University Press (OUP)
Subject
Animal Science and Zoology,Food Animals
Link
http://academic.oup.com/af/article-pdf/9/3/6/32412403/vfz013.pdf
Reference27 articles.
1. Precision engineering for PRRSV resistance in pigs: macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function;Burkard;Plos Pathog,2017
2. Pigs lacking the scavenger receptor cysteine-rich domain 5 of CD163 are resistant to porcine reproductive and respiratory syndrome virus 1 Infection;Burkard;J. Virol,2018
3. CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses;Calvert;J. Virol,2007
4. Efficient TALEN-mediated gene knockout in livestock;Carlson;Proc. Natl. Acad. Sci,2012
5. The possibility of positive selection for both F18(+)escherichia coli and stress resistant pigs opens new perspectives for pig breeding;Coddens;Vet. Microbiol,2008
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