Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever-Reference-Cited by-同舟云学术

Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever

Published:2020-04-21 Issue:5 Volume:7 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Fuller Risa¹^ORCID,Moshier Erin²,Jacobs Samantha E¹,Tremblay Douglas³,Lancman Guido³,Coltoff Alexander³,Caro Jessica³,Mascarenhas John³,Rana Meenakshi¹

Affiliation:

1. Division of Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA

2. TCI Biostatistics Shared Resource Facility, Institute for Healthcare Delivery Science, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA

3. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA

Abstract

Abstract We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofaa138/33111218/ofaa138.pdf

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