Digital technologies represent the fastest, broadest, and deepest technical change experienced in international development, affecting every sector. Inclusive and accessible technology increases access by persons with disabilities to markets, spaces, and services. This has raised opportunities as well as the stakes, to ensure that technology-driven development is inclusive of the diverse needs of persons with disabilities. Digital ecosystems can evolve to advance toward the social inclusion, economic self-sufficiency, and resilience of persons with disabilities. There are success stories, but also continuing inequities and gaps in access, affordability, and usage of technology by persons with disabilities. Ultimately, investments in infrastructure, skills, regulation, and institutions are necessary to ensure accessible and inclusive digital development.