Concise enantioselective synthesis of wine lactone via intramolecular Diels–Alder reaction-Reference-Cited by-同舟云学术

Concise enantioselective synthesis of wine lactone via intramolecular Diels–Alder reaction

Published:2021-03-15 Issue:6 Volume:85 Page:1390-1394
ISSN:1347-6947
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Ohkubo Yasutaka¹²,Masuda Yui²,Ogura Yusuke¹^ORCID,Takikawa Hirosato¹^ORCID,Watanabe Hidenori¹

Affiliation:

1. Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

2. Technical Research Institute, R&D Center, T. Hasegawa Co., Ltd., Kawasaki, Kanagawa, Japan

Abstract

ABSTRACT An enantioselective synthesis of (3S,3aS,7aR)-wine lactone, a major aroma component of white wine and citrus juices, was achieved starting from (S)-2-methyl-3-butenoic acid. An intramolecular Diels–Alder reaction was employed as a key step.

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

http://academic.oup.com/bbb/advance-article-pdf/doi/10.1093/bbb/zbab045/37742800/zbab045.pdf

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