Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD—Prediction and Prevention of Inflammatory Bowel Disease

Author:

Torres Joana12,Halfvarson Jonas3,Rodríguez-Lago Iago4ORCID,Hedin Charlotte R H56ORCID,Jess Tine78,Dubinsky Marla9,Croitoru Kenneth1011,Colombel Jean-Frédéric12ORCID

Affiliation:

1. Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal

2. Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

3. Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

4. Department of Gastroenterology, Hospital de Galdakao, and Biocruces Bizkaia Health Research Institute, Bilbao, Spain

5. Karolinska Institutet, Department of Medicine Solna, Stockholm, Sweden

6. Karolinska University Hospital, Gastroenterology unit, Department of Gastroenterology, Dermatovenereology and Rheumatology, Stockholm, Sweden

7. Department of Epidemiology Research, Statens Serum Institut, Copenhagen S, Denmark

8. PREDICT, Institute of Clinical Medicine, Aalborg University, Aalborg, Denmark

9. Division of Pediatric Gastroenterology and Nutrition, Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center, Icahn School of Medicine Mount Sinai, New York, NY, USA

10. Center for Inflammatory Bowel Disease, Mount Sinai Hospital, Toronto, ON, Canada

11. Division of Gastroenterology and Hepatology, University of Toronto, Toronto, ON, Canada

12. Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Abstract

Abstract Inflammatory bowel disease [IBD] is a complex chronic disorder with no clear aetiology and no known cure. Despite recent advances in overall disease management and improved therapeutics, patients with IBD still experience a substantial burden. Furthermore, as the incidence continues to increase in developing areas of the world, it is expected that the burden of IBD to society will increase and exert tremendous pressure on health care systems worldwide. Therefore, new strategies to prevent the global increase of IBD are urgently required. Data are being progressively acquired on the period preceding disease diagnosis, which support the concept that IBD has a preclinical period that may reveal the triggers of disease and may be amenable to early intervention. Having a better knowledge of this preclinical period will increase the potential not only for improved understanding of disease pathogenesis and improved therapeutics, but also for disease prediction and prevention.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

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