Vedolizumab-Associated Pancreatitis in Paediatric Ulcerative Colitis: Functional Selectivity of the α4β7integrin and MAdCAM-1 Pathway?
Author:
Affiliation:
1. Department of Gastroenterology, Sydney Children’s Hospital, New South Wales, Australia
2. School of Women and Children’s Health, University of New South Wales, New South Wales, Australia
Publisher
Oxford University Press (OUP)
Subject
Gastroenterology,General Medicine
Link
http://academic.oup.com/ecco-jcc/article-pdf/12/4/507/24468285/jjx167.pdf
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2. The binding specificity and selective antagonism of vedolizumab, an anti-α4β7 integrin therapeutic antibody in development for inflammatory bowel diseases;Soler;J Pharmacol Exp Ther,2009
3. Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice;Yang;Diabetes,1997
4. Aberrant activation of integrin α4β7 suppresses lymphocyte migration to the gut;Park;J Clin Invest,2007
5. Rheostat regulation of integrin-mediated leukocyte adhesion;Douglas;J Clin Invest,2007
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