Miltefosine-resistant Leishmania infantum strains with an impaired MT/ROS3 transporter complex retain amphotericin B susceptibility
Author:
Affiliation:
1. Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk, Belgium
Funder
FWO
University of Antwerp
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)
Link
http://academic.oup.com/jac/article-pdf/73/2/392/23610359/dkx407.pdf
Reference18 articles.
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2. Increasing failure of miltefosine in the treatment of kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance;Rijal;Clin Infect Dis,2013
3. Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from India;Srivastava;Parasit Vectors,2017
4. Genomic and molecular characterization of miltefosine resistance in Leishmania infantum strains with either natural or acquired resistance through experimental selection of intracellular amastigotes;Mondelaers;PLoS One,2016
5. Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug;Perez-Victoria;Antimicrob Agents Chemother,2003
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