Semaglutide for weight loss in people with obesity as an adjunctive treatment for hidradenitis suppurativa: its impact on disease control and quality of life

Author:

Lyons Daniel1ORCID,Louly Nathan Anusha1ORCID,Pender Emily1,Murray Gregg1,Smith Conor23ORCID,Kirby Brian12,Hughes Rosalind12

Affiliation:

1. Department of Dermatology, St Vincent’s University Hospital , Dublin , Ireland

2. Charles Institute of Dermatology, University College Dublin , Belfield, Dublin , Ireland

3. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin , Ireland

Abstract

Hidradenitis suppurativa (HS) has a significant impact on patients’ quality of life (QoL) and mortality. We report the use of semaglutide and its impact on disease control and QoL in 30 patients with obesity attending an HS specialty clinic. These retrospective data suggest that the addition of semaglutide to standard HS treatments results in improvement in QoL and fewer HS flares. The retrospective nature of the study is a limitation. Placebo-controlled randomized clinical trials should be done in HS to assess the efficacy of semaglutide in this debilitating condition.

Publisher

Oxford University Press (OUP)

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