Relationship between hindgut microbes and feed conversion ratio in Hu sheep and microbial longitudinal development
Author:
Xu Dan1, Cheng Jiangbo1ORCID, Zhang Deyin2, Huang Kai2, Zhang Yukun2, Li Xiaolong1, Zhao Yuan2, Zhao Liming1, Wang Jianghui1, Lin Changchun1, Yang Xiaobin1, Zhai Rui1, Cui Panpan1, Zeng Xiwen1, Huang Yongliang1, Ma Zongwu1, Liu Jia1, Han Kunchao2, Liu Xiaoqiang1, Yang Fan1, Tian Huibin2, Weng Xiuxiu2, Zhang Xiaoxue1, Wang Weimin2
Affiliation:
1. College of Animal Science and Technology, Gansu Agricultural University , Lanzhou, Gansu 730070 , China 2. The State Key Laboratory of Grassland Agro-Ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University , Lanzhou, Gansu 730020 , China
Abstract
Abstract
Feed efficiency is an important indicator in the sheep production process, which plays an important role in improving economic benefits and strengthening energy conservation and emission reduction. Compared with the rumen, the fermentation of the hindgut microorganisms can also provide part of the energy for the host, and the composition of the hindgut microorganisms will affect the feed efficiency. Therefore, we hope to find new ways to regulate sheep feed efficiency by studying the sheep gut microbes. In this study, male Hu sheep with the same birth date were raised under the same conditions until 180 d old. The sheep were divided into high and low groups according to the feed conversion ratio (FCR) at 80 to 180 d old, and the differences in rectal microorganisms between the two groups were compared. The permutational multivariate analysis (PERMANOVA) test showed that there were differences in microorganisms between the two groups (P < 0.05). Combined with linear fitting analysis, a total of six biomarkers were identified, including Ruminobacter, Eubacterium_xylanophilum_group, Romboutsia, etc. Functional enrichment analysis showed that microorganisms may affect FCR through volatile fatty acids synthesis and inflammatory response. At the same time, we conducted a longitudinal analysis of the hindgut microbes, sampling nine-time points throughout the sheep birth to market stages. The microbiota is clearly divided into two parts: before weaning and after weaning, and after weaning microbes are less affected by before weaning microbial composition.
Publisher
Oxford University Press (OUP)
Subject
Genetics,Animal Science and Zoology,General Medicine,Food Science
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