Nutritional benefits, ethnomedicinal uses, phytochemistry, pharmacological properties and toxicity of Spondias mombin Linn: a comprehensive review

Author:

Ogunro Olalekan Bukunmi1ORCID,Oyeyinka Barnabas Oluwatomide2ORCID,Gyebi Gideon Ampoma3ORCID,Batiha Gaber El-Saber4ORCID

Affiliation:

1. Department of Biological Sciences, Faculty of Applied Sciences, KolaDaisi University , Ibadan , Nigeria

2. Department of Botany, Faculty of Science and Agriculture, University of Fort Hare , Alice 5700, Eastern Cape , South Africa

3. Department of Biochemistry, Faculty of Science and Technology Bingham University , Karu , Nigeria

4. Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University , AlBeheira , Egypt

Abstract

Abstract Objectives Spondias mombin is traditionally used as an herbal medicine for several human diseases and ailments in the tropical regions across the globe including the African countries. This study aimed to provide comprehensive information on nutritional benefits, ethnomedicinal uses, phytochemical constituents, pharmacological properties and toxicology study of S. mombin. Information was gathered from documented literatures in scientific database. Key findings The study revealed that S. mombin has nutritional values; with the leaf, fruit, flower, seed, and stem bark possessing a wide range of ethnomedicinal uses across several regions, with documented pharmacological properties. S. mombin has a frequent rate of ethnomedicinal utility in cases of abortion, constipation, fever, gonorrhea, postpartum hemorrhage, digestive pain, diarrhoea, dysentery and wounds. Ethnopharmacological studies showed that crude extracts and chemical compounds from S. mombin manifested in vivo and in vitro biological and pharmacological activities. About 102 isolated compounds from the leaf, fruit, or stem bark of S. mombin have been reported. Summary Overall, S. mombin has several nutritive and ethnomedicinal benefits owing to its chemical constituents, which are linkable to the several pharmacological activities. There remains however, the need for dosage intake caution, upon the advice of medical professionals.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

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