The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex-Reference-Cited by-同舟云学术

The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex

Published:2002-02-01 Issue:3 Volume:21 Page:231-239
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:

Author:

Budayova-Spano Monika¹,Lacroix Monique²,Thielens Nicole M.²,Arlaud Gérard J.²,Fontecilla-Camps Juan Carlos¹,Gaboriaud Christine¹

Affiliation:

1. Laboratoire de Cristallographie et Cristollogénèse des Protéines, Institut de Biologie Structurale Jean-Pierre Ebel, CEA-CNRS-UJF; 41 rue Jules Horowitz F-38027 Grenoble cedex 1 France

2. Laboratoire d'Enzymologie Moléculaire, Institut de Biologie Structurale Jean-Pierre Ebel, CEA-CNRS-UJF; 41 rue Jules Horowitz F-38027 Grenoble cedex 1 France

Publisher

Wiley

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Reference63 articles.

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2. Complete amino acid sequence of the A chain of human complement-classical-pathway enzyme C1r;Arlaud;Biochem J,1987a

3. A functional model of the human C1 complex;Arlaud;Immunol Today,1987b

4. The atypical serine proteases of the complement system;Arlaud;Adv Immunol,1998

5. The Protein Data Bank: a computer-based archival file for macromolecular structures;Bernstein;J Mol Biol,1977

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