Targeted Analysis of Serum Proteins Encoded at Known Inflammatory Bowel Disease Risk Loci

Author:

Drobin Kimi1,Assadi Ghazaleh2,Hong Mun-Gwan1,Andersson Eni1,Fredolini Claudia1,Forsström Björn1,Reznichenko Anna2,Akhter Tahmina2,Ek Weronica E23,Bonfiglio Ferdinando24,Hansen Mark Berner56,Sandberg Kristian78,Greco Dario9,Repsilber Dirk10,Schwenk Jochen M1,D’Amato Mauro211,Halfvarson Jonas12

Affiliation:

1. Affinity Proteomics, SciLifeLab, School of Biotechnology, KTH, Royal Institute of Technology, Stockholm, Sweden

2. Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden

3. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

4. Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastián, Spain

5. AstraZeneca R&D Mölndal, Innovative and Global Medicines, Mölndal, Sweden

6. Digestive Disease Center, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

7. Science for Life Laboratory, Drug Discovery & Development Platform & Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala Biomedical Center, Uppsala University, Uppsala, Sweden

8. Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

9. Institute of Biotechnology, University of Helsinki, Helsinki, Finland

10. School of Medical Sciences, Örebro University, Örebro, Sweden

11. BioDonostia Health Research Institute, San Sebastian and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain

12. Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

Funder

AstraZeneca

Örebro University Hospital Research Foundation

Swedish Knowledge Foundation

Knut and Alice Wallenberg Foundation

Erling-Persson Family Foundation

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Reference52 articles.

1. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review;Molodecky;Gastroenterology,2012

2. Inflammatory bowel disease;Kaser;Annu Rev Immunol,2010

3. The history of genetics in inflammatory bowel disease;Ek;Ann Gastroenterol,2014

4. Inherited determinants of Crohn’s disease and ulcerative colitis phenotypes: a genetic association study;Cleynen;Lancet,2016

5. Proteomics. Tissue-based map of the human proteome;Uhlén;Science,2015

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