Infants Younger Than 6 Months Infected With SARS-CoV-2 Show the Highest Respiratory Viral Loads
Author:
Ochoa Valeria1, Díaz Fernando Erra1, Ramirez Ezequiel1, Fentini María Clara1, Carobene Mauricio1, Geffner Jorge1, Arruvito Lourdes1, Remes Lenicov Federico1, Adamczyk Alan, Azzolina Sabrina, Baquero Lucía, Benencio Paula, Berini Carolina, Biglione Mirna, Bleichmar Lucía, Cabrerizo Gonzalo, Cassime Silvia, Cassime Ricardo, Ceballos Ana, Cevallos Cintia, Czernikier Alejandro, Delpino Victoria, Di Diego García Facundo, Ducasa Nicolás, Elizalde Mercedes, Flichman Diego, Gatti Ramiro, Ghiglione Yanina, Giannone Denise, Gómez Claudio, Gonzalez Polo Virginia, Laufer Natalia, Leicaj Luz, Longueira Yesica, Lopez Malizzia Alvaro, Mazzitelli Ignacio, Melucci Ganzarain Claudia, Montesano Fernando, Morando Nicolás, Ostrowski Matías, Pampuro Sandra, Paletta Ana, Pando María, Penas Federico, Pérez Paula, Piccardo Claudio, Pieralisi Azul, Pippo Mónica, Polo Laura, Quiroga Florencia, Sabatté Juan, Salvatori Melina, Sananes Inés, Seery Vanesa, Speroni Micaela, Turk Gabriela, Varese Augusto, Vecchione Belén, Vera Aguilar Douglas,
Affiliation:
1. Universidad de Buenos Aires-Instituto de Investigaciones Biomédicas en Retrovirus y SIDA, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina
Abstract
Abstract
There is a paucity of reports on the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in infants, because most studies have grouped infants with older children. We analyzed the viral loads of 45318 SARS-CoV-2–positive nasopharyngeal swab samples obtained in Buenos Aires, Argentina. Infants younger than 6 months presented higher viral loads than any other age group. Children older than 6 months showed significantly lower viral loads, similar to those founds in adults. This observation raises new questions regarding the role of infants in the spreading of SARS-CoV-2 infection.
Funder
University of Buenos Aires National Ministry of Science Technology and Innovation
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Immunology and Allergy
Cited by
14 articles.
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