Protein Phosphatase 1–Targeting Small-Molecule C31 Inhibits Ebola Virus Replication-Reference-Cited by-同舟云学术

Protein Phosphatase 1–Targeting Small-Molecule C31 Inhibits Ebola Virus Replication

Published:2018-08-28 Issue:suppl_5 Volume:218 Page:S627-S635
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Ammosova Tatiana¹²³,Pietzsch Colette A⁴⁵⁶,Saygideğer Yasemin⁷,Ilatovsky Andrey⁸,Lin Xionghao¹,Ivanov Andrey¹,Kumari Namita¹²,Jerebtsova Marina⁹,Kulkarni Amol¹⁰,Petukhov Michael⁸,Üren Aykut⁷,Bukreyev Alexander⁴⁵⁶,Nekhai Sergei¹²⁹

Affiliation:

1. Center for Sickle Cell Disease, Howard University

2. Department of Medicine, Howard University

3. Yakut Science Center for Complex Medical Problems, Yakutsk

4. Department of Pathology, University of Texas Medical Branch at Galveston

5. Department of Microbiology and Immunology, University of Texas Medical Branch at Galveston

6. Galveston National Laboratory, University of Texas Medical Branch at Galveston

7. Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D. C

8. Division of Molecular and Radiation Biophysics, Petersburg Nuclear Physics Institute, St. Petersburg, Russia

9. Department of Microbiology, Howard University

10. College of Pharmacy, Howard University

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

http://academic.oup.com/jid/article-pdf/218/suppl_5/S627/26689872/jiy422.pdf

Reference18 articles.

1. Therapeutics for postexposure treatment of Ebola virus infection;Jerebtsova;Future Virol,2015

2. Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription;Ilinykh;J Biol Chem,2014

3. The Ebola virus nucleoprotein recruits the host PP2A-B56 phosphatase to activate transcriptional support activity of VP30;Kruse;Mol Cell,2018

4. The extended PP1 toolkit: designed to create specificity;Bollen;Trends Biochem Sci,2010

5. The PP1 binding code: a molecular-lego strategy that governs specificity;Heroes;FEBS J,2013

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