The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis

Published:2018-03-15 Issue:5 Volume:24 Page:1005-1020
ISSN:1078-0998
Container-title:Inflammatory Bowel Diseases
language:en
Short-container-title:

Author:

Rodriguez-Palacios Alexander¹,Harding Andrew¹,Menghini Paola¹,Himmelman Catherine¹,Retuerto Mauricio²,Nickerson Kourtney P³,Lam Minh¹,Croniger Colleen M⁴,McLean Mairi H⁵⁶,Durum Scott K⁵,Pizarro Theresa T⁷,Ghannoum Mahmoud A²,Ilic Sanja⁸,McDonald Christine³,Cominelli Fabio¹⁹

Affiliation:

1. Division of Gastroenterology and Liver Disease, Department of Medicine, School of Medicine, Cleveland, Ohio

2. Center for Medical Mycology, Department of Dermatology, School of Medicine, Cleveland, Ohio

3. Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio

4. Department of Nutrition, School of Medicine, Cleveland, Ohio

5. Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland

6. School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Scotland, UK

7. Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, Ohio

8. Department of Human Sciences and Human Nutrition, The Ohio State University, Columbus, Ohio

9. Digestive Health Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Link

http://academic.oup.com/ibdjournal/article-pdf/24/5/1005/25984137/izy060.pdf

Reference69 articles.

1. Worsening of bowel symptoms through diet in patients with inflammatory bowel disease;Eppinga;Inflamm Bowel Dis,2016

2. Diet and exacerbation of inflammatory bowel disease symptoms–food for thought;Limdi;Inflamm Bowel Dis,2016

3. Dietary practices and beliefs in patients with inflammatory bowel disease;Limdi;Inflamm Bowel Dis,2016

4. ESPEN guideline: clinical nutrition in inflammatory bowel disease;Forbes;Clin Nutr,2017

5. Environmental factors in inflammatory bowel disease: a case-control study based on a danish inception cohort;Hansen;J Crohns Colitis,2011

Cited by 145 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ClonalParabacteroidesfrom Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn’s Disease Complications;2024-01-10

2. Consumption of sucralose- and acesulfame-potassium-containing diet soda alters the relative abundance of microbial taxa at the species level: findings of two pilot studies;Applied Physiology, Nutrition, and Metabolism;2024-01-01

3. The Microbiome, Metabolism, and Networks in Precision Nutrition;Precision Nutrition;2024

4. The microbiome and cardiovascular disease: Implications in Precision Medicine;Comprehensive Precision Medicine;2024

5. The Effects of Artificial Sweeteners on Intestinal Nutrient-Sensing Receptors: Dr. Jekyll or Mr. Hyde?;Life;2023-12-20