Impact of myocardial infarction symptom presentation on emergency response and survival

Author:

Møller Amalie Lykkemark1ORCID,Mills Elisabeth Helen Anna2ORCID,Gnesin Filip1ORCID,Jensen Britta3ORCID,Zylyftari Nertila4ORCID,Christensen Helle Collatz5,Blomberg Stig Nikolaj Fasmer56ORCID,Folke Fredrik456ORCID,Kragholm Kristian Hay7ORCID,Gislason Gunnar489ORCID,Fosbøl Emil10,Køber Lars610,Gerds Thomas Alexander11ORCID,Torp-Pedersen Christian12ORCID

Affiliation:

1. Department of Cardiology, Nordsjællands Hospital, Dyrehavevej 29, Hillerød 2400, Denmark

2. Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, Aalborg 9100, Denmark

3. Department of Health Science and Technology, Aalborg University, Niels Jernes Vej 14, Aalborg 9220, Denmark

4. Department of Cardiology, Copenhagen University Hospital Herlev and Gentofte, Gentofte Hospitalsvej 1, Hellerup 2900, Denmark

5. Copenhagen Emergency Medical Services, Telegrafvej 5, Ballerup 2750, Denmark

6. Department of Clinical Medicine, University of Copenhagen, Blegdamsvej 3B, Copenhagen 2200, Denmark

7. Unit of Clinical Biostatistics and Epidemiology, Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark

8. Department of Research, Danish Heart Foundation, Vognmagergade 7, Copenhagen 1120, Denmark

9. The National Institute of Public Health, University of Southern Denmark, Studiestræde 6, Copenhagen 1455, Denmark

10. Departmet of Cardiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark

11. Section of Biostatistics, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5A, 1353, Copenhagen, Denmark

Abstract

Abstract Aims We examined associations between symptom presentation and chance of receiving an emergency dispatch and 30-day mortality among patients with acute myocardial infarction (MI). Methods and results Copenhagen, Denmark has a 24-h non-emergency medical helpline and an emergency number 1-1-2 (equivalent to 9-1-1). Both services register symptoms/purpose of calls. Among patients with MI as either hospital diagnosis or cause of death within 72 h after a call, the primary symptom was categorized as chest pain, atypical symptoms (breathing problems, unclear problem, central nervous system symptoms, abdominal/back/urinary, other cardiac symptoms, and other atypical symptoms), unconsciousness, non-informative symptoms, and no recorded symptoms. We identified 4880 emergency and 3456 non-emergency calls from patients with MI. The most common symptom was chest pain (N = 5219) followed by breathing problems (N = 556). Among patients with chest pain, 95% (3337/3508) of emergency calls and 76% (1306/1711) of non-emergency calls received emergency dispatch. Mortality was 5% (163/3508) and 3% (49/1711) for emergency/non-emergency calls, respectively. For atypical symptoms 62% (554/900) and 17% (137/813) of emergency/non-emergency calls received emergency dispatch and mortality was 23% (206/900) and 15% (125/813). Among unconscious, patients 99%/100% received emergency dispatch and mortality was 71%/75% for emergency/non-emergency calls. Standardized 30-day mortality was 4.3% for chest pain and 15.6% for atypical symptoms, and associations between symptoms and emergency dispatch remained in subgroups of age and sex. Conclusion Myocardial infarction patients presenting with atypical symptoms when calling for help have a reduced chance of receiving an emergency dispatch and increased 30-day mortality compared to MI patients with chest pain.

Funder

The Danish Heart Foundation

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Critical Care and Intensive Care Medicine,General Medicine

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